This book presents an innovative, scientifically grounded approach to depression that draws on insights from neuroscience, biochemistry, physics, psychology, evolutionary biology, and economics, forming a multidisciplinary strategy not readily found online. It emphasizes addressing the root causes of depression for lasting change, offering a detailed, step-by-step guide to help individuals navigate life’s challenges. The approach redefines self-care, integrating a holistic wellness strategy that encompasses psychological, behavioral, and biochemical aspects, aiming to not only overcome depression but also promote overall well-being and sustainable self-improvement.